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C-C Chemokine Receptor Type 5 (CCR5) (N-Term) Peptide

Details for Product No. ABIN1381969
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Protein Name
Synonyms AM4-7, CD195, Cmkbr5, Ckr5, CC-CKR-5, CCR-5, CMKBR5, GPCR, CCR5, CCCKR5, CKR-5, CKR5, IDDM22
Protein Region
N-Term
Origin
Human
Application
Blocking Peptide (BP)
Pubmed 3 references available
Quantity 0.05 mg
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Catalog No. ABIN1381969
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Characteristics 15 amino amino terminus of human CCR5.
Human
Alternative Name CCR5
Research Area Cardiovascular, Atherosclerosis, Innate Immunity, Chemokines, Alzheimer's Disease, Receptors, CD Antigens, Signaling
Application Notes CCR5 peptide is used for blocking the activity of CCR5.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications Raport, Gosling, Schweickart et al.: "Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha." in: The Journal of biological chemistry, Vol. 271, Issue 29, pp. 17161-6, 1996 (PubMed).

Choe, Farzan, Sun et al.: "The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates." in: Cell, Vol. 85, Issue 7, pp. 1135-48, 1996 (PubMed).

He, Chen, Farzan et al.: "CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia." in: Nature, Vol. 385, Issue 6617, pp. 645-9, 1997 (PubMed).

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