Drought-Repressed 4 Protein (DR4) (C-Term) Peptide

Details for Product No. ABIN1381982, Supplier: Log in to see
Protein Name
  • APO2
  • CD261
  • DR4
  • TRAILR-1
  • TRAILR1
  • tumor necrosis factor receptor superfamily, member 10a
  • TNFRSF10A
Protein Region
C-Term
Origin
Human
3
2
Application
Blocking Peptide (BP)
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Blocked Antibody anti-DR4 antibody (Drought-Repressed 4 Protein) (C-Term) (ABIN1030366)
Characteristics 19 amino acids near the carboxy terminus of human DR4.
Human
Research Area Immunology, Innate Immunity, Cytokines, Apoptosis/Necrosis, Death Receptors, Signaling
Application Notes DR4 peptide is used for blocking the activity of DR4.
Restrictions For Research Use only
Format Liquid
Concentration 200 μg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications Mizui, Yamazaki, Sagane, Tanaka: "cDNA cloning of mouse tumor necrosis factor-alpha converting enzyme (TACE) and partial analysis of its promoter." in: Gene, Vol. 233, Issue 1-2, pp. 67-74, 1999 (PubMed).

Peschon, Slack, Reddy, Stocking, Sunnarborg, Lee, Russell, Castner, Johnson, Fitzner, Boyce, Nelson, Kozlosky, Wolfson, Rauch, Cerretti, Paxton, March, Black: "An essential role for ectodomain shedding in mammalian development." in: Science (New York, N.Y.), Vol. 282, Issue 5392, pp. 1281-4, 1998 (PubMed).

Pan, ORourke, Chinnaiyan, Gentz, Ebner, Ni, Dixit: "The receptor for the cytotoxic ligand TRAIL." in: Science (New York, N.Y.), Vol. 276, Issue 5309, pp. 111-3, 1997 (PubMed).