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DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA) (C-Term) Peptide

Details for Product No. ABIN1381983, Supplier: Log in to see
Protein Name
  • DFFA
  • DFF-45
  • DFF1
  • ICAD
  • A330085O09Rik
  • DFF35
  • Dff45
  • ICAD-L
  • ICAD-S
  • DNA fragmentation factor, 45kDa, alpha polypeptide
  • DNA fragmentation factor, alpha subunit
  • DFFA
  • dffa
  • Dffa
Protein Region
C-Term
Origin
Human
6
2
2
Application
Blocking Peptide (BP)
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Blocked Antibody anti-DFFA antibody (DNA Fragmentation Factor, 45kDa, alpha Polypeptide) (C-Term) (ABIN1030360)
Characteristics 19 amino acids near the carboxy terminus of human DFF45.
Human
Research Area Apoptosis/Necrosis, DNA/RNA
Application Notes DFF45 peptide is used for blocking the activity of DFF45.
Restrictions For Research Use only
Format Liquid
Concentration 200 μg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications Liu, Zou, Slaughter, Wang: "DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis." in: Cell, Vol. 89, Issue 2, pp. 175-84, 1997 (PubMed).

Sanicola, Hession, Worley, Carmillo, Ehrenfels, Walus, Robinson, Jaworski, Wei, Tizard, Whitty, Pepinsky, Cate: "Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 12, pp. 6238-43, 1997 (PubMed).

Buj-Bello, Adu, Piñón, Horton, Thompson, Rosenthal, Chinchetru, Buchman, Davies: "Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase." in: Nature, Vol. 387, Issue 6634, pp. 721-4, 1997 (PubMed).