CASP8 and FADD-Like Apoptosis Regulator (CFLAR) (C-Term) Peptide

Details for Product No. ABIN1382005
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Protein Name
Synonyms
CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1, 2310024N18Rik, A430105C05Rik, Cash, ENSMUSG00000072980, Flip, Gm9845, c-Flip, Clarp1, cfl ... show more
CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1, 2310024N18Rik, A430105C05Rik, Cash, ENSMUSG00000072980, Flip, Gm9845, c-Flip, Clarp1, cflar, CFLAR, DKFZp469E1815 show less
Protein Region
C-Term
Origin
Human
(5), (2), (1)
Application
Blocking Peptide (BP)
Pubmed 3 references available
Catalog no. ABIN1382005
Quantity 0.05 mg
Price
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Characteristics 19 amino acids near the carboxy terminus of human FLIP.
Human
Alternative Name FLIP
Research Area Cancer, Apoptosis/Necrosis, Signaling
Application Notes FLIP peptide is used for blocking the activity of FLIP.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Storage -20 °C
Expiry Date 12 months
Background publications Irmler, Thome, Hahne et al.: "Inhibition of death receptor signals by cellular FLIP." in: Nature, Vol. 388, Issue 6638, pp. 190-5, 1997 (PubMed).

Li, Nijhawan, Budihardjo et al.: "Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade." in: Cell, Vol. 91, Issue 4, pp. 479-89, 1997 (PubMed).

Hu, Benedict, Wu et al.: "Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 8, pp. 4386-91, 1998 (PubMed).

Reactivities (5), (2), (1)
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