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Caspase 12 (CASP12) (N-Term) Peptide

Details for Product No. ABIN1382069, Supplier: Log in to see
Protein Name
  • Caspase-12
Protein Region
N-Term
Origin
Mouse (Murine)
2
1
Application
Blocking Peptide (BP)
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Blocked Antibody anti-Caspase 12 (CASP12) (N-Term) antibody (ABIN1031295)
Characteristics 16 amino amino terminus of mouse Caspase-12.
Mouse
Research Area Apoptosis/Necrosis
Application Notes Caspase-12 peptide is used for blocking the. activity of caspase-12.
Restrictions For Research Use only
Format Liquid
Concentration 200 μg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications McConnell, Vertino: "Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1." in: Cancer research, Vol. 60, Issue 22, pp. 6243-7, 2000

Nakagawa, Zhu, Morishima, Li, Xu, Yankner, Yuan: "Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta." in: Nature, Vol. 403, Issue 6765, pp. 98-103, 2000

Conway, McConnell, Bowring, Donald, Warren, Vertino: "TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers." in: Cancer research, Vol. 60, Issue 22, pp. 6236-42, 2000