Caspase-12 (Large) (Large Isoform) Peptide

Details for Product No. ABIN1382158
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Protein Name
Protein Region
Large Isoform
Origin
Mouse (Murine)
Application
Blocking Peptide (BP)
Pubmed 3 references available
Quantity 0.05 mg
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Catalog No. ABIN1382158
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Characteristics 18 amino acids within the large cleavage product of murine caspase-12.
Mouse
Application Notes Caspase-12 peptide is used for blocking the activity of the Caspase-12.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications Molloy, Bresnahan, Leppla et al.: "Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen." in: The Journal of biological chemistry, Vol. 267, Issue 23, pp. 16396-402, 1992 (PubMed).

Duesbery, Webb, Leppla et al.: "Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor." in: Science (New York, N.Y.), Vol. 280, Issue 5364, pp. 734-7, 1998 (PubMed).

Nakagawa, Zhu, Morishima et al.: "Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta." in: Nature, Vol. 403, Issue 6765, pp. 98-103, 2000 (PubMed).

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