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Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (C-Term) Peptide

Details for Product No. ABIN1382253
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Protein Name
Synonyms AW556805, Mcl-1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, TM, bcl2-L-3, mcl1/EAT, mcl-1
Protein Region
C-Term
Origin
Human
(1), (1), (3), (1), (1), (1)
Application
Blocking Peptide (BP)
Pubmed 3 references available
Quantity 0.05 mg
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Catalog No. ABIN1382253
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Characteristics 15 amino acids near the carboxy terminus of human Mcl-1.
Human
Alternative Name Mcl-1
Research Area Cancer, Apoptosis/Necrosis
Application Notes Mcl-1 peptide is used for blocking the activity of Mcl-1.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications Kozopas, Yang, Buchan et al.: "MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 8, pp. 3516-20, 1993 (PubMed).

Yang, Ramanathan, Muthumani et al.: "Induction of inflammation by West Nile virus capsid through the caspase-9 apoptotic pathway." in: Emerging infectious diseases, Vol. 8, Issue 12, pp. 1379-84, 2002 (PubMed).

Chu, Ng: "Interaction of West Nile virus with alpha v beta 3 integrin mediates virus entry into cells." in: The Journal of biological chemistry, Vol. 279, Issue 52, pp. 54533-41, 2004 (PubMed).

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