Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5) (N-Term) Peptide

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Protein Name
Synonyms 7420452D20Rik, ASK, ASK1, MAPKKK5, Mekk5, mitogen-activated protein kinase kinase kinase 5, MUD21.11, MUD21_11, MEKK5, MAP3K5
Protein Region
(2), (6), (3), (3)
Blocking Peptide (BP)
Pubmed 4 references available
Quantity 0.05 mg
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Availability Will be delivered in 2 to 3 Business Days
Characteristics 16 amino acids near the amino terminus of human ASK1.
Alternative Name ASK1
Research Area Cardiovascular, Hypertrophy, Apoptosis/Necrosis
Application Notes ASK1 peptide is used for blocking the activity of ASK1.
Restrictions For Research Use only
Format Liquid
Concentration 200 μg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications Davies, Mak, Young et al.: "TRAF6 is required for TRAF2-dependent CD40 signal transduction in nonhemopoietic cells." in: Molecular and cellular biology, Vol. 25, Issue 22, pp. 9806-19, 2005 (PubMed).

Grech, Amesbury, Chan et al.: "TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells." in: Immunity, Vol. 21, Issue 5, pp. 629-42, 2004 (PubMed).

Kuai, Nickbarg, Wooters et al.: "Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 14363-9, 2003 (PubMed).

Wang, Diener, Jannuzzi et al.: "Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase." in: The Journal of biological chemistry, Vol. 271, Issue 49, pp. 31607-11, 1997 (PubMed).

Catalog No. ABIN1382332
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