Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2) (Middle Region) Peptide
CASP2
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all Caspase 2 (CASP2) products
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
- Protein Region
- Middle Region
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DNANCPSLQN KPKMFFIQAC RGDETDRGVD QQDGKNHTQS PGCEESDAGK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Casp2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
- Synonyms
- xCaspase-2 Peptide, Caspase-2 Peptide, ICH-1 Peptide, Nedd2 Peptide, CASP-2 Peptide, ICH1 Peptide, NEDD-2 Peptide, NEDD2 Peptide, PPP1R57 Peptide, ICH-1L/1S Peptide, ICH1L1S Peptide, caspase 2 Peptide, caspase 2 L homeolog Peptide, caspase-2 Peptide, CASP2 Peptide, casp2.L Peptide, CpipJ_CPIJ008254 Peptide, Casp2 Peptide
- Background
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Casp2 is involved in the activation cascade of caspases responsible for apoptosis execution. It might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. It may be important in multistep carcinogenesis.
Alias Symbols: Caspase-2, ICH-1, Nedd2
Protein Size: 452 - Molecular Weight
- 51 kDa
- Gene ID
- 12366
- NCBI Accession
- NM_007610, NP_031636
- UniProt
- P29594
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