Cerebral Dopamine Neurotrophic Factor (CDNF) (N-Term) Peptide
CDNF
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CDNF products
- CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IDRGVNFSLD TIEKELISFC LDTKGKENRL CYYLGATKDA ATKILSEVTR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CDNF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
- Synonyms
- ARMETL1 Peptide, 9330140G23 Peptide, Armetl1 Peptide, cerebral dopamine neurotrophic factor Peptide, CDNF Peptide, Cdnf Peptide
- Background
-
CDNF is a trophic factor for dopamine neurons. CDNF prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, CDNF restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.
Alias Symbols: ARMETL1
Protein Size: 187 - Molecular Weight
- 21 kDa
- Gene ID
- 441549
- NCBI Accession
- NM_001029954, NP_001025125
- UniProt
- Q49AH0
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