NFKB Activating Protein (NKAP) (C-Term) Peptide
NKAP
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NKAP products
- NKAP (NFKB Activating Protein (NKAP))
- Protein Region
- C-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EAVRLRKENQ IYSADEKRAL ASFNQEERRK RENKILASFR EMVYRKTKGK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NKAP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NKAP (NFKB Activating Protein (NKAP))
- Synonyms
- DSMA4 Peptide, GEF720 Peptide, Syx Peptide, Tech Peptide, c6orf194l Peptide, wu:fj36d09 Peptide, wu:fj49c09 Peptide, 2610020O08Rik Peptide, AA987160 Peptide, AI849147 Peptide, AL024236 Peptide, 2610020o08rik Peptide, nkap Peptide, NKAPL Peptide, NFKB activating protein Peptide, pleckstrin homology and RhoGEF domain containing G5 Peptide, NFKB activating protein S homeolog Peptide, NKAP Peptide, PLEKHG5 Peptide, nkap Peptide, Nkap Peptide, nkap.S Peptide
- Background
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This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.
Alias Symbols: FLJ22626
Protein Size: 415 - Molecular Weight
- 46 kDa
- Gene ID
- 79576
- NCBI Accession
- NM_024528, NP_078804
- UniProt
- Q8N5F7
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