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Left-Right Determination Factor 2 (LEFTY2) (N-Term) Peptide

LEFTY2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN2184307
  • Target See all LEFTY2 products
    LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    AGPGAALTEE QLLGSLLRQL QLSEVPVLDR ADMEKLVIPA HVRAQYVVLL
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-LEFTY2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))
    Synonyms
    EBAF Peptide, LEFTA Peptide, LEFTYA Peptide, TGFB4 Peptide, AI450052 Peptide, Ebaf Peptide, Leftb Peptide, Stra3 Peptide, Tgfb4 Peptide, lefty Peptide, lefty-1 Peptide, atv2 Peptide, cb720 Peptide, fe38b03 Peptide, wu:fe38b03 Peptide, 6030463A22Rik Peptide, AV214969 Peptide, Lefta Peptide, Ebaf2 Peptide, left-right determination factor 2 Peptide, left right determination factor 1 Peptide, lefty2 Peptide, Left-right determination factor 2 Peptide, left-right determination factor 2-like Peptide, LEFTY2 Peptide, Lefty1 Peptide, lft2 Peptide, Lefty2 Peptide, LOC699676 Peptide, LOC100232580 Peptide
    Background
    LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in its gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of its gene in the endometrium.

    Alias Symbols: EBAF, LEFTA, LEFTYA, TGFB4

    Protein Size: 366
    Molecular Weight
    40 kDa
    Gene ID
    7044
    NCBI Accession
    NM_003240, NP_003231
    UniProt
    O00292
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