Left-Right Determination Factor 2 (LEFTY2) (N-Term) Peptide
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- Target See all LEFTY2 products
- LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AGPGAALTEE QLLGSLLRQL QLSEVPVLDR ADMEKLVIPA HVRAQYVVLL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-LEFTY2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))
- Synonyms
- EBAF Peptide, LEFTA Peptide, LEFTYA Peptide, TGFB4 Peptide, AI450052 Peptide, Ebaf Peptide, Leftb Peptide, Stra3 Peptide, Tgfb4 Peptide, lefty Peptide, lefty-1 Peptide, atv2 Peptide, cb720 Peptide, fe38b03 Peptide, wu:fe38b03 Peptide, 6030463A22Rik Peptide, AV214969 Peptide, Lefta Peptide, Ebaf2 Peptide, left-right determination factor 2 Peptide, left right determination factor 1 Peptide, lefty2 Peptide, Left-right determination factor 2 Peptide, left-right determination factor 2-like Peptide, LEFTY2 Peptide, Lefty1 Peptide, lft2 Peptide, Lefty2 Peptide, LOC699676 Peptide, LOC100232580 Peptide
- Background
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LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in its gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of its gene in the endometrium.
Alias Symbols: EBAF, LEFTA, LEFTYA, TGFB4
Protein Size: 366 - Molecular Weight
- 40 kDa
- Gene ID
- 7044
- NCBI Accession
- NM_003240, NP_003231
- UniProt
- O00292
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