GRB2-Related Adaptor Protein (GRAP) (N-Term) Peptide

Details for Product No. ABIN2184413, Supplier: Log in to see
Protein Name
  • 8430435N19Rik
  • BB233594
  • GRAP
  • grap
  • zgc:110202
  • MGC109892
  • si:dkeyp-9d4.1
  • Grap
  • GRB2-related adaptor protein
  • GRB2-related adapter protein
  • GRB2-related adaptor protein a
  • GRB2-related adaptor protein b
  • GRAP
  • Grap
  • LOC489534
  • grapa
  • grapb
  • LOC100727005
Protein Region
N-Term
Origin
Human
3
2
1
1
1
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Blocked Antibody anti-GRAP antibody (GRB2-Related Adaptor Protein) (N-Term) (ABIN2791566)
Sequence SDELAFNKGD TLKILNMEDD QNWYKAELRG VEGFIPKNYI RVKPHPWYSG
Characteristics This is a synthetic peptide designed for use in combination with antiGRAP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligandactivated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCRABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its Nterminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

Alias Symbols: -

Protein Size: 217
Molecular Weight 25 kDa
Gene ID 10750
NCBI Accession NM_006613, NP_006604
UniProt Q13588
Research Area Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeat freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at 20C. Avoid repeat freezethaw cycles.