TIMP Metallopeptidase Inhibitor 1 (TIMP1) (N-Term) Peptide
TIMP1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TIMP1 products
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QRYEIKMTKM YKGFQALGDA ADIRFVYTPA MESVCGYFHR SHNRSEEFLI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TIMP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
- Synonyms
- TIMP-1 Peptide, TIMP1 Peptide, DKFZp468A0912 Peptide, CLGI Peptide, EPA Peptide, EPO Peptide, HCI Peptide, TIMP Peptide, Timp Peptide, Clgi Peptide, TIMP metallopeptidase inhibitor 1 Peptide, tissue inhibitor of metalloproteinase 1 Peptide, TIMP1 Peptide, Timp1 Peptide
- Background
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This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
Alias Symbols: CLGI, EPA, HCI, TIMP
Protein Size: 207 - Molecular Weight
- 22 kDa
- Gene ID
- 7076
- NCBI Accession
- NM_003254, NP_003245
- UniProt
- Q6FGX5
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