Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) (C-Term) Peptide
WNT1
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all WNT1 products
- WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
- Protein Region
- C-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NFCTYSGRLG TAGTAGRACN SSSPALDGCE LLCCGRGHRT RTQRVTERCN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Wnt1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
- Synonyms
- Xint-1 Peptide, Xwnt1 Peptide, int-1 Peptide, int1 Peptide, wnt-1 Peptide, wnt1-a Peptide, Int-1 Peptide, Wnt-1 Peptide, sw Peptide, swaying Peptide, BMND16 Peptide, INT1 Peptide, OI15 Peptide, Int1 Peptide, WNT-1 Peptide, sb:eu647 Peptide, zgc:194464 Peptide, zgc:194478 Peptide, WNT1 Peptide, Wnt family member 1 Peptide, Wnt family member 1 L homeolog Peptide, wingless-type MMTV integration site family, member 1 Peptide, WNT1 Peptide, wnt1.L Peptide, Wnt1 Peptide, wnt1 Peptide
- Background
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Wnt1 is a ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, it is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. It is a probable developmental protein and may be a signaling molecule important in CNS development. Wnt1 is likely to signal over only few cell diameters. It ha s a proeminent role in the induction of the mesencephalon and cerebellum. It may play a crucial role in the morphogenesis of the neural tube and/or the early stages of CNS development. It has a role in osteoblast function and bone development.
Alias Symbols: Int-1, Wnt-1, sw, swaying
Protein Size: 370 - Molecular Weight
- 40 kDa
- Gene ID
- 22408
- NCBI Accession
- NM_021279, NP_067254
- UniProt
- P04426
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