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F-Box and WD Repeat Domain Containing 7 (FBXW7) Peptide
| Name | F-Box and WD Repeat Domain Containing 7 (FBXW7) |
| Synonyms | AGO, CDC4, FBW6, FBW7, FBX30, FBXW6, SEL10, FBXO30, SEL-10, FLJ16457, DKFZp686F23254, cdc4 |
| Catalog no. | ABIN265228 |
| Quantity | 50 µg (Lot specific) |
| Price | 195.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics | Synonyms: FBW7, FBX30, SEL10, Archipelago homolog, hAgo, SEL-10, hCDC4, F-box/WDrepeat-containing protein 7, F-box and WD-40 domain-containing protein 7, F-box proteinFBX30 |
| Swiss-Prot | Q969H0 |
| Immunogen | Synthetic peptide dervied from the human FBXW7 protein |
| Description | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-proteinligase complex which mediates the ubiquitination and subsequent proteasomaldegradation of target proteins. Probably recognizes and binds to phosphorylated targetproteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellulardomain (NICD), and probably PSEN1. |
| Specificity | Control peptide for antibodies ABIN265229 andd ABIN265230 only. Add. Information: Molecular Weight: 80 kDa |
Application Details
| Application Notes | Western blot. Positive Control: Widely expressed in most human tissues. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Concentration | Lot specific |
| Purification | Purified |
| Buffer | Phosphate buffered saline with 0.08% sodium azide |
| Storage | Store at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Restrictions | For Research Use only |
