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Tachykinin Receptor 1 (TACR1) Peptide

Details for Product No. ABIN268372
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Protein Name
Source
Synthetic
Application
Blocking Peptide (BP)
Pubmed 7 references available
Quantity 0.05 mg
Shipping to United States (Change)
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Catalog No. ABIN268372
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Specificity This peptide is specific for NB300-101 only.
Background The tachykinins belong to an evolutionary conserved family of peptide neurotransmittersthat share the c-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an establishedrole in neurotransmission. The mammalian tachykinins include substance P, neurokinin.
Gene Symbol: TACR1
Gene ID 6869
Research Area Hormones, Receptors
Application Notes Used as a blocking peptide for NB 300-101
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer Peptide dissolved in dH2O. Contains no BSA.
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage -80 °C
Storage Comment -80 °C.
General Vigna, Bowden, McDonald et al.: "Characterization of antibodies to the rat substance P (NK-1) receptor and to a chimeric substance P receptor expressed in mammalian cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 14, Issue 2, pp. 834-45, 1994 (PubMed).

Mantyh, Allen, Ghilardi et al.: "Rapid endocytosis of a G protein-coupled receptor: substance P evoked internalization of its receptor in the rat striatum in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 7, pp. 2622-6, 1995 (PubMed).

Mantyh, DeMaster, Malhotra et al.: "Receptor endocytosis and dendrite reshaping in spinal neurons after somatosensory stimulation." in: Science (New York, N.Y.), Vol. 268, Issue 5217, pp. 1629-32, 1995 (PubMed).

Mantyh, Rogers, Ghilardi et al.: "Differential expression of two isoforms of the neurokinin-1 (substance P) receptor in vivo." in: Brain research, Vol. 719, Issue 1-2, pp. 8-13, 1997 (PubMed).

Mantyh, Pappas, Lapp et al.: "Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum." in: Gastroenterology, Vol. 111, Issue 5, pp. 1272-80, 1996 (PubMed).

Allen, Rogers, Ghilardi et al.: "Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 17, Issue 15, pp. 5921-7, 1997 (PubMed).

Mantyh, Rogers, Honore et al.: "Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor." in: Science (New York, N.Y.), Vol. 278, Issue 5336, pp. 275-9, 1997 (PubMed).

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