Amyloid beta (Abeta) (AA 25-35) peptide (Biotin)

Details for Product No. ABIN2958526, Supplier: Log in to see
Protein Name
  • aaa
  • abeta
  • abpp
  • ad1
  • appi
  • ctfgamma
  • cvap
  • pn2
  • APP
  • ABPP
  • amyloid beta (A4) precursor protein
  • app
  • APP
Protein Region
AA 25-35
Origin
Human
36
5
4
4
3
2
2
1
1
1
Source
Synthetic
Purification tag / Conjugate
This beta Amyloid peptide is labelled with Biotin.
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Sequence Modified GSNKGAIIGL M
Characteristics Amyloid beta (25-35), N-Alpha-Biot-LC Labeled
Purity The purity was determined to be >95 % by HPLC analysis.
Background Amyloid peptides, derived from amyloid precursor protein (APP), are thought to play a role in the development of the senile plaques associated with Alzheimer's Disease. The amyloid hypothesis presupposes that flaws in the processing of APP result in abnormally high levels of the longer, "stickier" forms of beta amyloid, known as Abeta42 and Abeta43, leading to aggregation of amyloid in the neuronal cell death and ultimately neuronal death. Mutations in the structure of Abeta40 and related peptides as well as in some of the enzymes involved in the processing of APP have been shown to alter the processing of APP. The sporadic (i.e., non-genetic) form of the disease, however, is far more common, caused by aging in concert with a number of both genetic and environmental risk factors.
Molecular Weight 1399.71
Research Area Neurology, Alzheimer's Disease
Restrictions For Research Use only
Format Lyophilized
Buffer The peptide supplied in trifluroacetate salt as a lyophilized powder.
Handling Advice For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Storage -20 °C
Storage Comment Store product at -20 °C. For optimal storage, aliquot diluted product into smaller quantities and store at recommended temperature.