Glial Fibrillary Acidic Protein (GFAP) Peptide

Details for Product No. ABIN495053
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Protein Name
Synonyms AI836096, cb345, etID36982.3, gfapl, wu:fb34h11, wu:fk42c12, xx:af506734, zgc:110485, GFAP
Application
Control Peptide (CP)
Pubmed 5 references available
Catalog no. ABIN495053
Quantity 0.1 mg
Price
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Specificity Phospho-GFAP-pS8 Antibody Blocking Peptide
Alternative Name GFAP
Background GFAP is one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system.
Alternate names: Glial Fibrillary Acidic Protein
Molecular Weight 1804.38 Da.
Gene ID 2670
NCBI Accession NP_001124491
UniProt P14136
Research Area Stem Cells, Cytoskeleton, Glia marker, Cell/Tissue Markers, Neurology
Comment

This peptide is for ABIN358488

Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 0.1 mL DI water
Concentration 1,0 mg/mL
Buffer Lyophilized with 100% acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Nielsen, Holm, Johansen et al.: "A new splice variant of glial fibrillary acidic protein, GFAP epsilon, interacts with the presenilin proteins." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 29983-91, 2002 (PubMed).

Lopez-Egido, Cunningham, Berg et al.: "Menin's interaction with glial fibrillary acidic protein and vimentin suggests a role for the intermediate filament network in regulating menin activity." in: Experimental cell research, Vol. 278, Issue 2, pp. 175-83, 2002 (PubMed).

Namekawa, Takiyama, Aoki et al.: "Identification of GFAP gene mutation in hereditary adult-onset Alexander's disease." in: Annals of neurology, Vol. 52, Issue 6, pp. 779-85, 2002 (PubMed).

Shiroma, Kanazawa, Kato et al.: "Molecular genetic study in Japanese patients with Alexander disease: a novel mutation, R79L." in: Brain & development, Vol. 25, Issue 2, pp. 116-21, 2003 (PubMed).

Quintanar, Franco, Salinas: "Detection of glial fibrillary acidic protein and neurofilaments in the cerebrospinal fluid of patients with neurocysticercosis." in: Parasitology research, Vol. 90, Issue 4, pp. 261-3, 2003 (PubMed).

Reactivities (1), (1), (2), (1), (2)
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