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Details for Product No. ABIN495215

Sirtuin 5 (SIRT5) Peptide

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Protein Name
Synonyms SIR2L5, AV001953, 0610012J09Rik, 1500032M05Rik, zgc:92288, sirt5-a, SIRT5, sir2l5
Application
Control Peptide (CP)
Pubmed 2 references available
Catalog no. ABIN495215
Quantity 0.1 mg
Price
165.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Specificity SIRT5 Antibody (C-term) Blocking Peptide
Alternative Name SIRT5
Background SIRT5 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
Alternate names: NAD-dependent deacetylase sirtuin-5, SIR2-like protein 5, SIR2L5, SIRT-5, sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae), sirtuin 5, sirtuin type 5, sirtuin-5
Molecular Weight 1879.52 Da.
Gene ID 23408
NCBI Accession NP_036373.1
UniProt Q9NXA8
Research Area Chromatin and Nuclear Signaling, Proteases
Comment

This peptide is for ABIN358734

Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 0.1 mL deionized water
Concentration 1,0 mg/mL
Buffer Lyophilized with 100% acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Frye: "Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity." in: Biochemical and biophysical research communications, Vol. 260, Issue 1, pp. 273-9, 1999 (PubMed).

Frye: "Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins." in: Biochemical and biophysical research communications, Vol. 273, Issue 2, pp. 793-8, 2000 (PubMed).

Alternatives for antigen "Sirtuin 5 (SIRT5)", type "Peptides"
Reactivities (2)
Beacon