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Sirtuin 6 (SIRT6) Peptide

Details for Product No. ABIN495216
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Protein Name
Application
Control Peptide (CP)
Pubmed 3 references available
Quantity 0.1 mg
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Catalog No. ABIN495216
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Specificity SIRT6 Antibody (C-term) Blocking Peptide
Alternative Name SIRT6
Background SIRT6 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
Alternate names: NAD-dependent deacetylase sirtuin-6, SIR2-like protein 6, SIR2L6, SIRT-6, sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae), sirtuin 6, sirtuin type 6, sirtuin-6
Molecular Weight 1667.32 Da.
Gene ID 51548
NCBI Accession NP_001180214.1
UniProt Q8N6T7
Research Area Cancer
Comment

This peptide is for ABIN358735

Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 0.1 mL deionized water
Concentration 1,0 mg/mL
Buffer Lyophilized with 100% acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Frye: "Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins." in: Biochemical and biophysical research communications, Vol. 273, Issue 2, pp. 793-8, 2000 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

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