Transforming Growth Factor beta Regulator 1 (TBRG1) Peptide

Details for Product No. ABIN495346
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Protein Name
Synonyms NIAM, TB-5, AA408552, AA409675, Niam, Tb-5, mFLJ00213, MGC89629
Control Peptide (CP)
Pubmed 2 references available
Catalog no. ABIN495346
Quantity 0.1 mg
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Specificity TBRG1 Antibody (N-term) Blocking Peptide
Alternative Name TBRG1 / NIAM
Background TBRG1 acts as a growth inhibitor. It can activate TP53/p53, cause G1 arrest and collaborate with CDKN2A to restrict proliferation, but it does not require either protein to inhibit DNA synthesis. TBRG1 redistributes CDKN2A into the nucleoplasm, and is involved in maintaining chromosomal stability.
Alternate names: Nuclear interactor of ARF and Mdm2, Transforming growth factor beta regulator 1
Molecular Weight 2150.05 Da.
Gene ID 84897
NCBI Accession NP_116200.2
UniProt Q3YBR2

This peptide is for ABIN358981

Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 0.1 mL DI water
Concentration 1,0 mg/mL
Buffer Lyophilized with 100% acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Babalola, Schultz: "Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta." in: Molecular reproduction and development, Vol. 41, Issue 2, pp. 133-9, 1995 (PubMed).

Tompkins, Hagen, Frazier et al.: "A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability." in: The Journal of biological chemistry, Vol. 282, Issue 2, pp. 1322-33, 2007 (PubMed).

Reactivities (1)
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