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Transforming Growth Factor beta Regulator 1 (TBRG1) Peptide

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Protein Name
(1), (1)
Control Peptide (CP)
Pubmed 2 references available
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Quantity 0.1 mg
Shipping to United States ( )
Specificity TBRG1 Antibody (N-term) Blocking Peptide
Purity 100 %
Background TBRG1 acts as a growth inhibitor. It can activate TP53/p53, cause G1 arrest and collaborate with CDKN2A to restrict proliferation, but it does not require either protein to inhibit DNA synthesis. TBRG1 redistributes CDKN2A into the nucleoplasm, and is involved in maintaining chromosomal stability.Synonyms: Nuclear interactor of ARF and Mdm2, Transforming growth factor beta regulator 1
Molecular Weight 2150.05 Da
Gene ID 84897
NCBI Accession NP_116200
UniProt Q3YBR2
Application Notes Optimal working dilution should be determined by the investigator.

This peptide is for ABIN358981

Restrictions For Research Use only
Reconstitution Restore with 0.1 mL DI water
Concentration 1.0 mg/mL
Buffer Lyophilized with 100 % acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Background publications Tompkins, Hagen, Frazier et al.: "A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability." in: The Journal of biological chemistry, Vol. 282, Issue 2, pp. 1322-33, 2007 (PubMed).

Babalola, Schultz: "Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta." in: Molecular reproduction and development, Vol. 41, Issue 2, pp. 133-9, 1995 (PubMed).

Catalog No. ABIN495346

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