Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) Peptide

Details for Product No. ABIN495441
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Protein Name
Origin
Human
(2), (1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 2 references available
Quantity 0.1 mg
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Catalog No. ABIN495441
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Specificity PDK4 Antibody (C-term) Blocking Peptide
Purity 100 %
Alternative Name PDK4
Background PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Alternate names: Pyruvate dehydrogenase kinase isoform 4, Pyruvate dehydrogenase lipoamide kinase isozyme 4 mitochondrial
Molecular Weight 1654.86 Da
Gene ID 5166
NCBI Accession NP_002603
UniProt Q16654
Research Area Signaling, Metabolism
Application Notes Optimal working dilution should be determined by the investigator.
Comment

This peptide is for ABIN359098

Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 0.1 mL deionized water
Concentration 1.0 mg/mL
Buffer Lyophilized with 100 % acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Expiry Date 12 months
Background publications Cantrell: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, 2001 (PubMed).

Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, 2001 (PubMed).

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