Cyclin A2 (CCNA2) Peptide

Details for Product No. ABIN495784
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Protein Name
Origin
Human
(1), (1), (1), (2)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 2 references available
Quantity 0.1 mg
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Availability Discontinued
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Catalog No. ABIN495784
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Specificity CCNA2 Antibody (C-term) Blocking Peptide
Purity 100 %
Alternative Name Cyclin A2
Background CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.
Alternate names: CCN1, CCNA, CCNA2, Cyclin A, Cyclin-A2
Molecular Weight 2034.8 Da
Gene ID 890
NCBI Accession NP_001228
UniProt P20248
Research Area Cell Cycle
Application Notes Optimal working dilution should be determined by the investigator.
Comment

This peptide is for ABIN359545

Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 0.1 mL deionized water
Concentration 1.0 mg/mL
Buffer Lyophilized with 100 % acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Expiry Date 12 months
Background publications Wang, Chenivesse, Henglein et al.: "Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma." in: Nature, Vol. 343, Issue 6258, pp. 555-7, 1990 (PubMed).

Henglein, Chenivesse, Wang et al.: "Structure and cell cycle-regulated transcription of the human cyclin A gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 12, pp. 5490-4, 1994 (PubMed).

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