Mitogen-Activated Protein Kinase 4 (MAPK4) Peptide

Details for Product No. ABIN495792
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Protein Name
Origin
Human
(1), (1), (1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 3 references available
Quantity 0.1 mg
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Catalog No. ABIN495792
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Specificity MAPK4 Antibody (N-term) Blocking Peptide
Purity 100 %
Alternative Name MAPK4 / ERK4
Background Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus where it phosphorylates nuclear targets.Synonyms: Extracellular signal-regulated kinase 4, MAP kinase isoform p63, Mitogen-activated protein kinase 4, p63-MAPK
Molecular Weight 1742.43 Da
Gene ID 5596
NCBI Accession NP_002738
UniProt P31152
Application Notes Optimal working dilution should be determined by the investigator.
Comment

This peptide is for ABIN359555

Restrictions For Research Use only
Reconstitution Restore with 0.1 mL DI water
Concentration 1.0 mg/mL
Buffer Lyophilized with 100 % acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Background publications Seger, Krebs: "The MAPK signaling cascade." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 9, Issue 9, pp. 726-35, 1995 (PubMed).

Kant, Schumacher, Singh et al.: "Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5." in: The Journal of biological chemistry, Vol. 281, Issue 46, pp. 35511-9, 2006 (PubMed).

Lerner-Marmarosh, Miralem, Gibbs et al.: "Human biliverdin reductase is an ERK activator; hBVR is an ERK nuclear transporter and is required for MAPK signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 19, pp. 6870-5, 2008 (PubMed).

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