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Details for Product No. ABIN495792

Mitogen-Activated Protein Kinase 4 (MAPK4) Peptide

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Protein Name
Synonyms ERK-4, ERK3, Erk4, MAPK 4, PRKM4, p63MAPK, erk4, zgc:55498, wu:fi27d11
Application
Control Peptide (CP)
Pubmed 3 references available
Catalog no. ABIN495792
Quantity 0.1 mg
Price
165.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Specificity MAPK4 Antibody (N-term) Blocking Peptide
Alternative Name MAPK4 / ERK4
Background Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus where it phosphorylates nuclear targets.
Alternate names: Extracellular signal-regulated kinase 4, MAP kinase isoform p63, Mitogen-activated protein kinase 4, p63-MAPK
Molecular Weight 1742.43 Da.
Gene ID 5596
NCBI Accession NP_002738
UniProt P31152
Comment

This peptide is for ABIN359555

Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 0.1 mL DI water
Concentration 1,0 mg/mL
Buffer Lyophilized with 100% acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Seger, Krebs: "The MAPK signaling cascade." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 9, Issue 9, pp. 726-35, 1995 (PubMed).

Kant, Schumacher, Singh et al.: "Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5." in: The Journal of biological chemistry, Vol. 281, Issue 46, pp. 35511-9, 2006 (PubMed).

Lerner-Marmarosh, Miralem, Gibbs et al.: "Human biliverdin reductase is an ERK activator; hBVR is an ERK nuclear transporter and is required for MAPK signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 19, pp. 6870-5, 2008 (PubMed).

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