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Details for Product No. ABIN495845

Sprouty Homolog 4 Peptide

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Protein Name
Application
Control Peptide (CP)
Pubmed 3 references available
Catalog no. ABIN495845
Quantity 0.1 mg
Price
165.00 $   Plus shipping costs $45.00
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Specificity SPRY4 Antibody (Human C-term) Blocking Peptide
Alternative Name Sprouty homolog 4 / SPRY4
Background SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. The protein is positioned upstream of RAS activation and impairs the formation of active GTP-RAS.
Alternate names: Sprouty 4, Spry-4
Molecular Weight 1650.21 Da.
Gene ID 81848
NCBI Accession NP_001120968.1
UniProt Q9C004
Comment

This peptide is for ABIN359610

Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 0.1 mL DI water
Concentration 1,0 mg/mL
Buffer Lyophilized with 100% acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Tsumura, Toshima, Leeksma et al.: "Sprouty-4 negatively regulates cell spreading by inhibiting the kinase activity of testicular protein kinase." in: The Biochemical journal, Vol. 387, Issue Pt 3, pp. 627-37, 2005 (PubMed).

Wolf-Yadlin, Hautaniemi, Lauffenburger et al.: "Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 14, pp. 5860-5, 2007 (PubMed).

Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

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