Kringle Containing Transmembrane Protein 1 (KREMEN1) Peptide

Details for Product No. ABIN495986
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Protein Name
Application
Control Peptide (CP)
Pubmed 2 references available
Quantity 0.1 mg
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Catalog No. ABIN495986
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Specificity KREMEN1 Antibody (N-term) Blocking Peptide
Alternative Name Kremen protein 1
Background KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. This protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.
Alternate names: Dickkopf receptor, KREMEN, KREMEN1, KRM1, Kringle domain-containing transmembrane protein 1, Kringle-containing protein marking the eye and the nose
Molecular Weight 1688.27 Da.
Gene ID 83999
NCBI Accession NP_001034659
UniProt Q96MU8
Comment

This peptide is for ABIN359770

Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 0.1 mL DI water
Concentration 1,0 mg/mL
Buffer Lyophilized with 100% acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Kammeraat, Veldstra: "Characterization of succinate semialdehyde dehydrogenase from rat brain." in: Biochimica et biophysica acta, Vol. 151, Issue 1, pp. 1-10 (PubMed).

Mao, Wu, Davidson et al.: "Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling." in: Nature, Vol. 417, Issue 6889, pp. 664-7, 2002 (PubMed).

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