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Kringle Containing Transmembrane Protein 1 (KREMEN1) Peptide

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Protein Name
Origin
Human
(4), (1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 2 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability
Specificity KREMEN1 Antibody (N-term) Blocking Peptide
Purity 100 %
Background KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. This protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.Synonyms: Dickkopf receptor, KREMEN, KREMEN1, KRM1, Kringle domain-containing transmembrane protein 1, Kringle-containing protein marking the eye and the nose
Molecular Weight 1688.27 Da
Gene ID 83999
NCBI Accession NP_001034659
UniProt Q96MU8
Application Notes Optimal working dilution should be determined by the investigator.
Comment

This peptide is for ABIN359770

Restrictions For Research Use only
Reconstitution Restore with 0.1 mL DI water
Concentration 1.0 mg/mL
Buffer Lyophilized with 100 % acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Background publications Mao, Wu, Davidson et al.: "Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling." in: Nature, Vol. 417, Issue 6889, pp. 664-7, 2002 (PubMed).

Kammeraat, Veldstra: "Characterization of succinate semialdehyde dehydrogenase from rat brain." in: Biochimica et biophysica acta, Vol. 151, Issue 1, pp. 1-10 (PubMed).

Catalog No. ABIN495986

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