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Details for Product No. ABIN496393

Pim-1 Oncogene (PIM1) Peptide

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Protein Name
Synonyms PIM, pim-1, Pim-1, pim2, cb1068, fj47b05, wu:fj47b05, PIM1, pim, pim3
Control Peptide (CP)
Pubmed 5 references available
Catalog no. ABIN496393
Quantity 0.1 mg
165.00 $   Plus shipping costs $45.00
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Specificity PIM1 Antibody Blocking Peptide
Alternative Name PIM1
Background PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells. The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer. It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.
Alternate names: Pim-1, Proto-oncogene serine/threonine-protein kinase pim-1
Gene ID 5292
NCBI Accession NP_002639.1
UniProt P11309
Research Area Cancer, Hematopoietic Progenitors

This peptide is for ABIN360328

Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 0.1 mL DI water
Concentration 1,0 mg/mL
Buffer Lyophilized with 100% acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Reeves, Spies, Kiefer et al.: "Primary structure of the putative human oncogene, pim-1." in: Gene, Vol. 90, Issue 2, pp. 303-7, 1990 (PubMed).

Telerman, Amson, Zakut-Houri et al.: "Identification of the human pim-1 gene product as a 33-kilodalton cytoplasmic protein with tyrosine kinase activity." in: Molecular and cellular biology, Vol. 8, Issue 4, pp. 1498-503, 1988 (PubMed).

Koike, Maita, Taira et al.: "Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1)." in: FEBS letters, Vol. 467, Issue 1, pp. 17-21, 2000 (PubMed).

Pasqualucci, Neumeister, Goossens et al.: "Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas." in: Nature, Vol. 412, Issue 6844, pp. 341-6, 2001 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Alternatives for antigen "Pim-1 Oncogene (PIM1)", type "Peptides"
Reactivities (1), (1)