Guanine Nucleotide Binding Protein (G Protein) alpha 12 (GNA12) Peptide

Details for Product No. ABIN496505
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Protein Name
Synonyms NNX3, RMP, gep, AI414047, AI504261, Galpha12, gna12, gna12l
Control Peptide (CP)
Pubmed 5 references available
Catalog no. ABIN496505
Quantity 0.1 mg
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Specificity GNA12 Antibody Blocking Peptide
Alternative Name G protein subunit alpha 12 / GNA12
Background Guanine nucleotide-binding proteins (G proteins) are modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 subunits, alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
Alternate names: G alpha-12, Guanine nucleotide-binding protein subunit alpha-12
Molecular Weight 1623.36 Da.
Gene ID 2768
NCBI Accession NP_031379.2
UniProt Q03113

This peptide is for ABIN360476

Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 0.1 mL DI water
Concentration 1,0 mg/mL
Buffer Lyophilized with 100% acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
Expiry Date 12 months
Background publications Suzuki, Nakamura, Mano et al.: "Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 2, pp. 733-8, 2003 (PubMed).

Yamaguchi, Katoh, Negishi: "N-terminal short sequences of alpha subunits of the G12 family determine selective coupling to receptors." in: The Journal of biological chemistry, Vol. 278, Issue 17, pp. 14936-9, 2003 (PubMed).

Scherer, Cheung, MacDonald et al.: "Human chromosome 7: DNA sequence and biology...." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, 2003 (PubMed).

Hillier, Fulton, Fulton et al.: "The DNA sequence of human chromosome 7." in: Nature, Vol. 424, Issue 6945, pp. 157-64, 2003 (PubMed).

Krakstad, Ardawatia, Aragay: "A role for Galpha12/Galpha13 in p120ctn regulation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 28, pp. 10314-9, 2004 (PubMed).

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