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Corin, Serine Peptidase (CORIN) Peptide

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Protein Name
(2), (1), (1)
Control Peptide (CP)
Pubmed 1 reference available
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Quantity 0.1 mg
Shipping to United States ( )
Specificity CORIN Antibody (Center) Blocking Peptide
Purity 100 %
Background CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. This protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.Synonyms: ATC2, Atrial natriuretic peptide-converting enzyme, CRN, Heart-specific serine proteinase ATC2, Pro-ANP-converting enzyme, TMPRSS10, Transmembrane protease serine 10
Molecular Weight 2152.76 Da
Gene ID 10699
NCBI Accession NP_006578
UniProt Q9Y5Q5
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Restore with 0.1 mL DI water
Concentration 1.0 mg/mL
Buffer Lyophilized with 100 % acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Fox, Collard, Shernan et al.: "Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting." in: Anesthesiology, Vol. 110, Issue 4, pp. 738-47, 2009 (PubMed).

Catalog No. ABIN496924

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