Corin, Serine Peptidase (CORIN) Peptide

Details for Product No. ABIN496924
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Protein Name
Origin
Human
(2), (1), (1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN496924
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Specificity CORIN Antibody (Center) Blocking Peptide
Purity 100 %
Alternative Name CORIN
Background CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. This protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.
Alternate names: ATC2, Atrial natriuretic peptide-converting enzyme, CRN, Heart-specific serine proteinase ATC2, Pro-ANP-converting enzyme, TMPRSS10, Transmembrane protease serine 10
Molecular Weight 2152.76 Da
Gene ID 10699
NCBI Accession NP_006578
UniProt Q9Y5Q5
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with 0.1 mL deionized water
Concentration 1.0 mg/mL
Buffer Lyophilized with 100 % acetonitrile
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Fox, Collard, Shernan et al.: "Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting." in: Anesthesiology, Vol. 110, Issue 4, pp. 738-47, 2009 (PubMed).

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