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ADAM Metallopeptidase Domain 10 (ADAM10) Peptide

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Protein Name
Origin
Human
(4), (2), (2), (2)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 2 references available
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Quantity 50 μg
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Specificity Control peptide for AP30017PU-N. Peptide consists of 17 amino acids near the carboxy terminus of human ADAM10.
Background Synonyms: Disintegrin and metalloproteinase domain-containing protein 10, KUZ, Kuzbanian protein homolog, MADM, Mammalian disintegrin-metalloprotease
Gene ID 102
NCBI Accession NP_001101
UniProt O14672
Research Area Proteases, Extracellular Matrix
Application Notes ADAM10 peptide is used for blocking the activity of Anti-ADAM10. Incubating the peptidewith equal volume of ADAM10 antibody for 30 min at 37 °C usually completely blocks theantibody activity in Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.
Background publications Cecconi, Alvarez-Bolado, Meyer et al.: "Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development." in: Cell, Vol. 94, Issue 6, pp. 727-37, 1998 (PubMed).

Zou, Henzel, Liu et al.: "Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3." in: Cell, Vol. 90, Issue 3, pp. 405-13, 1997 (PubMed).

Catalog No. ABIN499210

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