ADAM Metallopeptidase Domain 10 (ADAM10) Peptide

Details for Product No. ABIN499210
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Protein Name
Origin
Human
(1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 2 references available
Quantity 50 µg
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Catalog No. ABIN499210
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Specificity Control peptide for AP30017PU-N. Peptide consists of 17 amino acids near the carboxy terminus of human ADAM10.
Alternative Name CD156c / ADAM10
Background Alternate names: Disintegrin and metalloproteinase domain-containing protein 10, KUZ, Kuzbanian protein homolog, MADM, Mammalian disintegrin-metalloprotease
Gene ID 102
NCBI Accession NP_001101
UniProt O14672
Research Area Proteases, Extracellular Matrix
Application Notes ADAM10 peptide is used for blocking the activity of Anti-ADAM10. Incubating the peptidewith equal volume of ADAM10 antibody for 30 min at 37°C usually completely blocks theantibody activity in Western blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.
Expiry Date 12 months
Background publications Zou, Henzel, Liu et al.: "Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3." in: Cell, Vol. 90, Issue 3, pp. 405-13, 1997 (PubMed).

Cecconi, Alvarez-Bolado, Meyer et al.: "Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development." in: Cell, Vol. 94, Issue 6, pp. 727-37, 1998 (PubMed).

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