Autophagy/beclin-1 Regulator 1 (AMBRA1) Peptide

Details for Product No. ABIN499272
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Protein Name
Origin
Human
(2)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN499272
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Specificity Control peptide for AP30048PU-N. Peptide consists of 18 amino acids near the amino terminus of human Ambra1.
Alternative Name AMBRA1
Background Synonyms: Activating molecule in BECN1-regulated autophagy protein 1, KIAA1736
Gene ID 55626
NCBI Accession NP_060219
UniProt Q9C0C7
Research Area Cancer, Autophagy, Neurogenesis
Application Notes Ambra1 peptide is used for blocking the activity of Ambra1 antibody. It usually blocks theantibody activity completely in Western blot by incubating the peptide with equal volumeof antibody for 30 min at 37 °C.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.
Background publications Fimia, Stoykova, Romagnoli et al.: "Ambra1 regulates autophagy and development of the nervous system." in: Nature, Vol. 447, Issue 7148, pp. 1121-5, 2007 (PubMed).

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