Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Peptide

Details for Product No. ABIN499402
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Protein Name
Origin
Human
(5), (1), (4)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 4 references available
Quantity 50 μg
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Catalog No. ABIN499402
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Specificity 15 amino acids near the carboxy terminus of human BAFF Receptor.
Purification purified
Alternative Name CD268 / BAFFR
Background Alternate names: B cell-activating factor receptor, BAFF receptor, BAFF-R, BLyS receptor 3, BR3, TNFRSF13C, Tumor necrosis factor receptor superfamily member 13C
Gene ID 115650
NCBI Accession NP_443177
UniProt Q96RJ3
Research Area Apoptosis/Necrosis, Receptors
Application Notes BAFF receptor peptide is used for blocking the antibody activity of BAFF-R. It usually blocksthe antibody activity completely in Western blot by incubating the peptide with equalvolume of antibody for 30 min at 37°C. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C.
Expiry Date 12 months
Background publications Tschopp, Martinon, Burns: "NALPs: a novel protein family involved in inflammation." in: Nature reviews. Molecular cell biology, Vol. 4, Issue 2, pp. 95-104, 2003 (PubMed).

Agostini, Martinon, Burns et al.: "NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder." in: Immunity, Vol. 20, Issue 3, pp. 319-25, 2004 (PubMed).

Bruey, Bruey-Sedano, Newman et al.: "PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 51897-907, 2004 (PubMed).

Martinon, Tschopp: "NLRs join TLRs as innate sensors of pathogens." in: Trends in immunology, Vol. 26, Issue 8, pp. 447-54, 2005 (PubMed).

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