Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) Peptide

Details for Product No. ABIN499436
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Protein Name
Origin
Human
(3)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 5 references available
Quantity 50 μg
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Availability Discontinued
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Catalog No. ABIN499436
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Specificity 16 amino acids near the carboxy terminus of human BCMA.
Purification purified
Alternative Name CD269 / BCMA
Background Synonyms: B-cell maturation protein, BCM, TNFRSF17, Tumor necrosis factor receptor superfamily member 17
Gene ID 608
NCBI Accession NP_001183
UniProt Q02223
Application Notes BCMA peptide is used for blocking the antibody activity of BCMA. It usually blocks theantibody activity completely in Western blot by incubating the peptide with equal volumeof antibody for 30 min at 37 °C.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C.
Background publications Pomerantz, Baltimore: "NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase." in: The EMBO journal, Vol. 18, Issue 23, pp. 6694-704, 2000 (PubMed).

Tojima, Fujimoto, Delhase et al.: "NAK is an IkappaB kinase-activating kinase." in: Nature, Vol. 404, Issue 6779, pp. 778-82, 2000 (PubMed).

Bonnard, Mirtsos, Suzuki et al.: "Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription." in: The EMBO journal, Vol. 19, Issue 18, pp. 4976-85, 2000 (PubMed).

Rao, Kadesch: "The intracellular form of notch blocks transforming growth factor beta-mediated growth arrest in Mv1Lu epithelial cells." in: Molecular and cellular biology, Vol. 23, Issue 18, pp. 6694-701, 2003 (PubMed).

Angelone, Quintieri, Amodio et al.: "Endocrine orchestration of cardiovascular, gastrointestinal and hypothalamic control." in: Current medicinal chemistry, Vol. 18, Issue 32, pp. 4976-86, 2011 (PubMed).

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