BMI1 Polycomb Ring Finger Oncogene (BMI1) Peptide

Details for Product No. ABIN499482
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Protein Name
Origin
Human
(4), (1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 3 references available
Quantity 50 μg
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Catalog No. ABIN499482
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Specificity 15 amino acids near the center of human BMI-1.
Purification purified
Alternative Name BMI-1 / RNF51
Background Alternate names: BMI1, PCGF4, Polycomb group RING finger protein 4, RING finger protein 51
Gene ID 100532731
NCBI Accession NP_001190991
UniProt P35226
Application Notes BMI-1 peptide is used for blocking the activity of BMI-1 antibody. It usually blocks theantibody activity completely in Western blot by incubating the peptide with equal volumeof antibody for 30 min at 37°C. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C.
Expiry Date 12 months
Background publications Wang, Diener, Jannuzzi et al.: "Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase." in: The Journal of biological chemistry, Vol. 271, Issue 49, pp. 31607-11, 1997 (PubMed).

Ichijo, Nishida, Irie et al.: "Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways." in: Science (New York, N.Y.), Vol. 275, Issue 5296, pp. 90-4, 1997 (PubMed).

Tobiume, Inage, Takeda et al.: "Molecular cloning and characterization of the mouse apoptosis signal-regulating kinase 1." in: Biochemical and biophysical research communications, Vol. 239, Issue 3, pp. 905-10, 1997 (PubMed).

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