Chemokine (C-X-C Motif) Receptor 6 (CXCR6) Peptide

Details for Product No. ABIN499486
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Protein Name
Origin
Human
(5), (1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 4 references available
Quantity 50 µg
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Catalog No. ABIN499486
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Specificity 15 amino amino terminus of human Bonzo.
Purification purified
Alternative Name CD186 / CXCR6
Background Alternate names: BONZO, CDw186, CXC-R6, CXCR-6, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, STRL33, TYMSTR
Gene ID 10663
NCBI Accession NP_006555
UniProt O00574
Research Area Chemokines, Receptors
Application Notes Bonzo peptide is used for blocking the activity of Anti-Bonzo. Incubating the peptide withequal volume of antibody for 30 min at 37°C usually completely blocks the antibodyactivity in Western blotting. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C.
Expiry Date 12 months
Background publications Willis, Jadayel, Du et al.: "Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types." in: Cell, Vol. 96, Issue 1, pp. 35-45, 1999 (PubMed).

Koseki, Inohara, Chen et al.: "CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 9955-61, 1999 (PubMed).

Thome, Martinon, Hofmann et al.: "Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 9962-8, 1999 (PubMed).

Yan, Lee, Schilbach et al.: "mE10, a novel caspase recruitment domain-containing proapoptotic molecule." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10287-92, 1999 (PubMed).

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