Checkpoint Kinase 2 (CHEK2) Peptide

Details for Product No. ABIN499618
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Protein Name
Origin
Human
(4), (1), (1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 4 references available
Quantity 50 μg
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Availability Discontinued
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Catalog No. ABIN499618
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Specificity 17 amino amino terminus of human Chk2.
Purification purified
Alternative Name CHK2
Background Alternate names: CHEK-2, CHEK2, CHK-2, CHK2 checkpoint homolog, Cds1, RAD53, Serine/threonine-protein kinase Chk2
Gene ID 11200
NCBI Accession NP_001005735
UniProt O96017
Application Notes Chk2 peptide is used for blocking the antibody activity of Chk2. It usually blocks theantibody activity completely in Western blot by incubating the peptide with equal volumeof antibody for 30 min at 37°C. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C.
Expiry Date 12 months
Background publications Geijtenbeek, Torensma, van Vliet et al.: "Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses." in: Cell, Vol. 100, Issue 5, pp. 575-85, 2000 (PubMed).

Geijtenbeek, Kwon, Torensma et al.: "DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells." in: Cell, Vol. 100, Issue 5, pp. 587-97, 2000 (PubMed).

Soilleux, Barten, Trowsdale: "DC-SIGN; a related gene, DC-SIGNR; and CD23 form a cluster on 19p13." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 6, pp. 2937-42, 2000 (PubMed).

Pöhlmann, Baribaud, Lee et al.: "DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus." in: Journal of virology, Vol. 75, Issue 10, pp. 4664-72, 2001 (PubMed).

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