Checkpoint Kinase 2 (CHEK2) Peptide

Details for Product No. ABIN499618
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Protein Name
(2), (9), (2), (3), (3), (1)
Control Peptide (CP)
Pubmed 4 references available
Quantity 50 μg
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Specificity 17 amino amino terminus of human Chk2.
Purification purified
Alternative Name CHK2
Background Synonyms: CHEK-2, CHEK2, CHK-2, CHK2 checkpoint homolog, Cds1, RAD53, Serine/threonine-protein kinase Chk2
Gene ID 11200
NCBI Accession NP_001005735
UniProt O96017
Application Notes Chk2 peptide is used for blocking the antibody activity of Chk2. It usually blocks theantibody activity completely in Western blot by incubating the peptide with equal volumeof antibody for 30 min at 37 °C.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C.
Background publications Pöhlmann, Baribaud, Lee et al.: "DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus." in: Journal of virology, Vol. 75, Issue 10, pp. 4664-72, 2001 (PubMed).

Soilleux, Barten, Trowsdale: "DC-SIGN; a related gene, DC-SIGNR; and CD23 form a cluster on 19p13." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 6, pp. 2937-42, 2000 (PubMed).

Geijtenbeek, Kwon, Torensma et al.: "DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells." in: Cell, Vol. 100, Issue 5, pp. 587-97, 2000 (PubMed).

Geijtenbeek, Torensma, van Vliet et al.: "Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses." in: Cell, Vol. 100, Issue 5, pp. 575-85, 2000 (PubMed).

Catalog No. ABIN499618
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