Complement C1q Tumor Necrosis Factor-Related Protein 6 (C1QTNF6) Peptide

Details for Product No. ABIN499676
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Protein Name
Origin
Human
(2)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 4 references available
Quantity 50 μg
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Availability Discontinued
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Catalog No. ABIN499676
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Specificity 15 amino acids near the carboxy terminus of human CTRP6.
Purification purified
Alternative Name C1QTNF6
Background Synonyms: CTRP6, Complement C1q tumor necrosis factor-related protein 6
Gene ID 114904
NCBI Accession NP_114116
UniProt Q9BXI9
Application Notes CTRP6 peptide is used for blocking the activity of CTRP6 antibody. It usually blocks theantibody activity completely in Western blot by incubating the peptide with equal volumeof antibody for 30 min at 37 °C.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Background publications Giovannone, Scaldaferri, Federici et al.: "Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential." in: Diabetes/metabolism research and reviews, Vol. 16, Issue 6, pp. 434-41, 2001 (PubMed).

Ozes, Akca, Mayo et al.: "A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 8, pp. 4640-5, 2001 (PubMed).

Shamji, Nghiem, Schreiber: "Integration of growth factor and nutrient signaling: implications for cancer biology." in: Molecular cell, Vol. 12, Issue 2, pp. 271-80, 2003 (PubMed).

Waters, Pessin: "Insulin receptor substrate 1 and 2 (IRS1 and IRS2): what a tangled web we weave." in: Trends in cell biology, Vol. 6, Issue 1, pp. 1-4, 2004 (PubMed).

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