Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) Peptide

Details for Product No. ABIN499691
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Protein Name
Origin
Human
(2)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 3 references available
Quantity 50 µg
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Catalog No. ABIN499691
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Specificity Amino acids 2 to 21 of Human CX3CR1 (1).
Purification purified
Alternative Name CX3CR1 / GPR13
Background Alternate names: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28
Gene ID 1524
NCBI Accession NP_001164642
UniProt P49238
Research Area Chemokines, Receptors
Application Notes CX3CR1 peptide is used for blocking the activity of Anti-CX3CR1. Incubating the peptidewith equal volume of CX3CR1 antibody for 30 min at 37°C usually completely blocks theantibody activity in Western blotting. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % BSA and 0.02 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C.
Expiry Date 12 months
Background publications Inohara, del Peso, Koseki et al.: "RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis." in: The Journal of biological chemistry, Vol. 273, Issue 20, pp. 12296-300, 1998 (PubMed).

McCarthy, Ni, Dixit: "RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase." in: The Journal of biological chemistry, Vol. 273, Issue 27, pp. 16968-75, 1998 (PubMed).

Thome, Hofmann, Burns et al.: "Identification of CARDIAK, a RIP-like kinase that associates with caspase-1." in: Current biology : CB, Vol. 8, Issue 15, pp. 885-8, 1998 (PubMed).

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