Death-Associated Protein Kinase 2 (DAPK2) Peptide

Details for Product No. ABIN499707
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Protein Name
Origin
Human
(1), (3), (2), (1), (1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 3 references available
Quantity 50 μg
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Catalog No. ABIN499707
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Specificity 15 amino acids near the carboxy terminus of human DAP kinase 2.
Purification purified
Alternative Name DAPK2 / DRP-1
Background Synonyms: DAP kinase 2, DAP-kinase-related protein 1, Death-associated protein kinase 2
Gene ID 23604
NCBI Accession NP_055141
UniProt Q9UIK4
Research Area Kinases/Phosphatases
Application Notes DAP kinase 2 peptide is used for blocking the antibody activity of DAP kinase 2. It usuallyblocks the antibody activity completely in Western blot by incubating the peptide withequal volume of antibody for 30 min at 37 °C.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C.
Background publications Yu, Huang, Shen et al.: "Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB." in: Current biology : CB, Vol. 9, Issue 10, pp. 539-42, 1999 (PubMed).

Sun, Lee, Navas et al.: "RIP3, a novel apoptosis-inducing kinase." in: The Journal of biological chemistry, Vol. 274, Issue 24, pp. 16871-5, 1999 (PubMed).

Pazdernik, Donner, Goebl et al.: "Mouse receptor interacting protein 3 does not contain a caspase-recruiting or a death domain but induces apoptosis and activates NF-kappaB." in: Molecular and cellular biology, Vol. 19, Issue 10, pp. 6500-8, 2000 (PubMed).

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