Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) Peptide

Details for Product No. ABIN499759
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Protein Name
Synonyms DR3, TR3, DDR3, LARD, APO-3, TRAMP, WSL-1, WSL-LR, TNFRSF12, Wsl, Tnfrsf12, TNFRSF25
Origin
Human
(5)
Application
Control Peptide (CP)
Pubmed 4 references available
Catalog no. ABIN499759
Quantity 50 µg
Price
170.50 $   Plus shipping costs $45.00
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Specificity 16 amino amino terminus of human DR3.
Alternative Name TNFRSF25 / DR3 / TRAMP
Background Alternate names: AIR, APO3, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, DDR3, Death receptor 3, LARD, Lymphocyte- associated receptor of death, Protein WSL, Protein WSL-1, TNFRSF12, Tumor necrosis factor receptor superfamily member 25, WSL, WSL1
Gene ID 8718
NCBI Accession NP_001034753.1
UniProt Q93038
Application Notes DR3 peptide is used for blocking the activity of Anti-DR3. Incubating the peptide with equalvolume of antibody for 30 min at 37°C usually completely blocks the antibody activity inWestern blotting. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20°C.
Expiry Date 12 months
Background publications Thome, Schneider, Hofmann et al.: "Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors." in: Nature, Vol. 386, Issue 6624, pp. 517-21, 1997 (PubMed).

Shu, Halpin, Goeddel: "Casper is a FADD- and caspase-related inducer of apoptosis." in: Immunity, Vol. 6, Issue 6, pp. 751-63, 1997 (PubMed).

Hu, Vincenz, Ni et al.: "I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis." in: The Journal of biological chemistry, Vol. 272, Issue 28, pp. 17255-7, 1997 (PubMed).

Irmler, Thome, Hahne et al.: "Inhibition of death receptor signals by cellular FLIP." in: Nature, Vol. 388, Issue 6638, pp. 190-5, 1997 (PubMed).

Reactivities (5)
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