interleukin 23, alpha subunit p19 (IL23A) Peptide

Details for Product No. ABIN499995
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Protein Name
Origin
Human
(2)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 3 references available
Quantity 50 μg
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Catalog No. ABIN499995
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Specificity 14 amino acids near the carboxy terminus of human IL-23.
Purification purified
Alternative Name Interleukin-23 alpha / IL23A
Background Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
Gene ID 51561
NCBI Accession NP_057668
UniProt Q9NPF7
Application Notes IL-23 peptide is used for blocking activity of IL-23 antibody. It usually blocks antibodyactivity completely in Western blot by incubating peptide with equal volume of antibody for30 min at 37 °C.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C.
Background publications Inohara, Ding, Chen et al.: "harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)." in: The EMBO journal, Vol. 16, Issue 7, pp. 1686-94, 1997 (PubMed).

Imaizumi, Tsuda, Imai et al.: "Molecular cloning of a novel polypeptide, DP5, induced during programmed neuronal death." in: The Journal of biological chemistry, Vol. 272, Issue 30, pp. 18842-8, 1997 (PubMed).

Lockshin, Osborne, Zakeri: "Cell death in the third millennium." in: Cell death and differentiation, Vol. 7, Issue 1, pp. 2-7, 2000 (PubMed).

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