Interleukin-1 Receptor-Associated Kinase 1 (IRAK1) Peptide

Details for Product No. ABIN500035
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Protein Name
Synonyms IRAK, pelle, Plpk, mPLK, IRAK-1, Il1rak, IRAK1-S, AA408924, RGD1563841, IRAK1
Origin
Human
(1), (1)
Application
Control Peptide (CP)
Pubmed 5 references available
Catalog no. ABIN500035
Quantity 50 µg
Price
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Specificity 13 amino acids near the carboxy terminus of human IRAK.
Alternative Name IRAK1
Background Alternate names: IRAK, IRAK-1, Interleukin-1 receptor-associated kinase 1
Gene ID 3654
NCBI Accession NP_001020413.1
UniProt P51617
Research Area Cytokines, Receptors, Inflammation
Application Notes IRAK peptide is used for blocking the activity of Anti-IRAK (CT). Incubating the peptide withequal volume of antibody for 30 min at 37°C usually completely blocks the activity ofAnti-IRAK in Western blotting. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20°C.
Expiry Date 12 months
Background publications Cao, Henzel, Gao: "IRAK: a kinase associated with the interleukin-1 receptor." in: Science (New York, N.Y.), Vol. 271, Issue 5252, pp. 1128-31, 1996 (PubMed).

Trofimova, Sprenkle, Green et al.: "Developmental and tissue-specific expression of mouse pelle-like protein kinase." in: The Journal of biological chemistry, Vol. 271, Issue 30, pp. 17609-12, 1996 (PubMed).

Robinson, Shibuya, Mui et al.: "IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB." in: Immunity, Vol. 7, Issue 4, pp. 571-81, 1997 (PubMed).

Huang, Gao, Li et al.: "Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 24, pp. 12829-32, 1998 (PubMed).

Yao, Li, Shi: "Optically active supramolecular complexes of water-soluble achiral polythiophenes and folic acid: spectroscopic studies and sensing applications." in: Langmuir : the ACS journal of surfaces and colloids, Vol. 24, Issue 22, pp. 12829-35, 2008 (PubMed).

Reactivities (1), (1)
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