Interferon Regulatory Factor 3 (IRF3) Peptide

Details for Product No. ABIN500053
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Protein Name
Control Peptide (CP)
Pubmed 4 references available
Quantity 50 μg
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Specificity 14 amino acids near the carboxy terminus of human IRF3.
Purification purified
Alternative Name IRF3
Background Synonyms: IRF-3, Interferon regulatory factor 3
Gene ID 3661
NCBI Accession NP_001562
UniProt Q14653
Research Area Immunology, Innate Immunity, Transcription Factors, Cytokines
Application Notes IRF3 peptide is used for blocking the activity of IRF3 antibody. It usually blocks theantibody activity completely in Western blot by incubating the peptide with equal volumeof antibody for 30 min at 37 °C.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Background publications Heiser, Labi, Erlacher et al.: "The Bcl-2 protein family and its role in the development of neoplastic disease." in: Experimental gerontology, Vol. 39, Issue 8, pp. 1125-35, 2004 (PubMed).

Cory, Huang, Adams: "The Bcl-2 family: roles in cell survival and oncogenesis." in: Oncogene, Vol. 22, Issue 53, pp. 8590-607, 2003 (PubMed).

Lockshin, Osborne, Zakeri: "Cell death in the third millennium." in: Cell death and differentiation, Vol. 7, Issue 1, pp. 2-7, 2000 (PubMed).

Hockenbery, Nuñez, Milliman et al.: "Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death." in: Nature, Vol. 348, Issue 6299, pp. 334-6, 1991 (PubMed).

Catalog No. ABIN500053
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