Interferon Regulatory Factor 3 (IRF3) Peptide

Details for Product No. ABIN500053
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Protein Name
Synonyms C920001K05Rik, IRF-3, IRF3, irf3
Origin
Human
(3)
Application
Control Peptide (CP)
Pubmed 4 references available
Catalog no. ABIN500053
Quantity 50 µg
Price
170.50 $   Plus shipping costs $45.00
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Specificity 14 amino acids near the carboxy terminus of human IRF3.
Alternative Name IRF3
Background Alternate names: IRF-3, Interferon regulatory factor 3
Gene ID 3661
NCBI Accession NP_001562.1
UniProt Q14653
Research Area Immunology, Innate Immunity, Transcription Factors, Cytokines
Application Notes IRF3 peptide is used for blocking the activity of IRF3 antibody. It usually blocks theantibody activity completely in Western blot by incubating the peptide with equal volumeof antibody for 30 min at 37°C. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Background publications Hockenbery, Nuñez, Milliman et al.: "Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death." in: Nature, Vol. 348, Issue 6299, pp. 334-6, 1991 (PubMed).

Lockshin, Osborne, Zakeri: "Cell death in the third millennium." in: Cell death and differentiation, Vol. 7, Issue 1, pp. 2-7, 2000 (PubMed).

Cory, Huang, Adams: "The Bcl-2 family: roles in cell survival and oncogenesis." in: Oncogene, Vol. 22, Issue 53, pp. 8590-607, 2003 (PubMed).

Heiser, Labi, Erlacher et al.: "The Bcl-2 protein family and its role in the development of neoplastic disease." in: Experimental gerontology, Vol. 39, Issue 8, pp. 1125-35, 2004 (PubMed).

Reactivities (3)
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