ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1) Peptide

Details for Product No. ABIN500418
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Protein Name
Origin
Human
(1), (5), (2), (1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN500418
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Specificity Control peptide for AP30631PU-N. Peptide consists of 18 amino acids near the amino terminus of human ORAI1.
Alternative Name ORAI1
Background Synonyms: CRACM1, Calcium release-activated calcium channel protein 1, ORAI-1, Protein orai-1, TMEM142A, Transmembrane protein 142A
Gene ID 84876
NCBI Accession NP_116179
UniProt Q96D31
Application Notes ORAI1 peptide is used for blocking the activity of ORAI1 antibody. It usually blocks theantibody activity completely in Western blot by incubating the peptide with equal volumeof antibody for 30 min at 37 °C.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Background publications Feske, Gwack, Prakriya et al.: "A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function." in: Nature, Vol. 441, Issue 7090, pp. 179-85, 2006 (PubMed).

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