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Presenilin 1 (PSEN1) Peptide

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Protein Name
Origin
Human
(10), (4), (2), (2), (2), (1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 1 reference available
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Quantity 50 μg
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Specificity Control peptide for AP30692PU-N. Peptide consists of 23 amino acids near the carboxy terminus of human presenilin1.
Background Synonyms: AD3, AF3, Alzheimer Disease 3, FAD, PS-1, PS1, PSEN1, PSNL1, Presenilin 1, S182
Gene ID 5663
NCBI Accession NP_000012
UniProt P49768
Research Area Alzheimer's Disease
Application Notes Presenilin1 peptide is used for blocking the activity of presenilin1 antibody. It usuallyblocks the antibody activity completely in Western blot by incubating the peptide withequal volume of antibody for 30 min at 37 °C.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Background publications Sherrington, Rogaev, Liang et al.: "Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. ..." in: Nature, Vol. 375, Issue 6534, pp. 754-60, 1995 (PubMed).

Catalog No. ABIN500538

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