CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) Peptide

Details for Product No. ABIN500562
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Protein Name
Origin
Human
(4)
Application
Control Peptide (CP)
Pubmed 4 references available
Quantity 50 µg
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Catalog No. ABIN500562
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Specificity 19 amino acids near the carboxy terminus of human RAIDD.
Alternative Name RAIDD
Background Alternate names: CRADD, Caspase and RIP adapter with death domain, Death domain-containing protein CRADD, RIP-associated protein with a death domain
Gene ID 8738
NCBI Accession NP_003796
UniProt P78560
Research Area Cancer, Apoptosis/Necrosis
Application Notes RAIDD peptide is used for blocking the activity of Anti-RAIDD. Incubating the peptide withequal volume of antibody for 30 min at 37°C usually completely blocks the antibodyactivity in Western blotting. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20°C.
Expiry Date 12 months
Background publications Deng, Liu, Ellmeier et al.: "Identification of a major co-receptor for primary isolates of HIV-1." in: Nature, Vol. 381, Issue 6584, pp. 661-6, 1996 (PubMed).

Dragic, Litwin, Allaway et al.: "HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5." in: Nature, Vol. 381, Issue 6584, pp. 667-73, 1996 (PubMed).

Dimitrov: "How do viruses enter cells? The HIV coreceptors teach us a lesson of complexity." in: Cell, Vol. 91, Issue 6, pp. 721-30, 1998 (PubMed).

Littman: "Chemokine receptors: keys to AIDS pathogenesis?" in: Cell, Vol. 93, Issue 5, pp. 677-80, 1998 (PubMed).

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