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Details for Product No. ABIN500783

Second Mitochondria-Derived Activator of Caspase (DIABLO) Peptide

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Protein Name
Synonyms Smac, DFNA64, SMAC, DBO, XSmac, smac, smac3, diablo-s
Origin
»Alternatives Mouse (Murine)
Application
Control Peptide (CP)
Pubmed 2 references available
Catalog no. ABIN500783
Quantity 50 µg
Price
159.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Specificity Control peptide for AP30815PU-N. Peptide consists of 16 amino acids near the carboxy terminus of mouse Smac.
Alternative Name DIABLO / SMAC
Background Alternate names: Diablo homolog mitochondrial, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase
Gene ID 66593
NCBI Accession NP_075721.3
UniProt Q9JIQ3
Application Notes Smac peptide is used for blocking the antibody activity of mSmac/DIABLO. It usuallyblocks the antibody activity completely in Western blot by incubating the peptide withequal volume of antibody for 30 min at 37°COther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20°C.
Expiry Date 12 months
Background publications Matsuoka, Huang, Elledge: "Linkage of ATM to cell cycle regulation by the Chk2 protein kinase." in: Science (New York, N.Y.), Vol. 282, Issue 5395, pp. 1893-7, 1998 (PubMed).

Tanaka, Arakawa, Yamaguchi et al.: "A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage." in: Nature, Vol. 404, Issue 6773, pp. 42-9, 2000 (PubMed).

Alternatives for antigen "Second Mitochondria-Derived Activator of Caspase (DIABLO)", type "Peptides"
Reactivities (2), (1)
Beacon