Suppressor of Cytokine Signaling 1 (SOCS1) Peptide

Details for Product No. ABIN500787
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Protein Name
Origin
Human
(1), (1), (5), (1), (1)
Source
Synthetic
Application
Control Peptide (CP)
Pubmed 2 references available
Quantity 50 µg
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Catalog No. ABIN500787
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Specificity Control peptide for AP30817PU-N. Peptide consists of 15 amino acids near the carboxy terminus of human SOCS1.
Alternative Name SOCS1
Background Alternate names: JAB, JAK-binding protein, SOCS-1, SSI-1, SSI1, STAT-induced STAT inhibitor 1, Suppressor of cytokine signaling 1, TIP-3, TIP3, Tec-interacting protein 3
Gene ID 8651
NCBI Accession NP_003736
Research Area Chromatin and Nuclear Signaling, Signaling, Cytokines
Application Notes SOCS1 peptide is used for blocking the activity of SOCS1 antibody. It usually blocks theantibody activity completely in Western blot by incubating the peptide with equal volumeof antibody for 30 min at 37°C. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Expiry Date 12 months
Background publications Yoshida, Matsui, Yamamoto et al.: "XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor." in: Cell, Vol. 107, Issue 7, pp. 881-91, 2002 (PubMed).

Calfon, Zeng, Urano et al.: "IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA." in: Nature, Vol. 415, Issue 6867, pp. 92-6, 2002 (PubMed).

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