Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) Peptide

Details for Product No. ABIN501029
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Protein Name
Origin
Human
(3), (1)
Application
Control Peptide (CP)
Pubmed 2 references available
Quantity 50 µg
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Catalog No. ABIN501029
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Specificity Control peptide for AP30939PU-N. Peptide consists of 17 amino acids near the carboxy terminus of human TRAIL.
Alternative Name CD253 / TRAIL
Background Alternate names: APO2L, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, TNFSF10, Tumor necrosis factor ligand superfamily member 10
Gene ID 8743
NCBI Accession NP_003801
Research Area Cancer, Apoptosis/Necrosis
Application Notes TRAIL peptide is used for blocking the activity of Anti-TRAIL. Incubating the peptide withequal volume of antibody for 30 min at 37°C usually completely blocks the activity ofAnti-TRAIL in Western blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20°C.
Expiry Date 12 months
Background publications Carpino, Wisniewski, Strife et al.: "p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells." in: Cell, Vol. 88, Issue 2, pp. 197-204, 1997 (PubMed).

Yamanashi, Baltimore: "Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok." in: Cell, Vol. 88, Issue 2, pp. 205-11, 1997 (PubMed).

Validation Images
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